Home Pipeline Historical Pipeline

Historical Pipeline

OPKO Biologics Projects Since 2006

(f.k.a ModigeneTech, Prolor Biotech)

MOD-101

2010-2011
Protein: Enbrel
Technology: CTP

Long-acting Enbrel (TNFR-FC) for treatment of autoimmune diseases by acting as a TNF inhibitor

MOD-201

2009-2010
Protein: GCSF
Technology: CTP

Long-acting GCSF for enhancing neutrophils and monocytes after chemotherapy, intended to replace the Filgrastim daily treatment

MOD-301

2012-2014
Protein: Factor IX
Technology: CTP

Long-acting coagulation factor IX as a replacement therapy for Hemophilia B patients

MOD-603

2010-2018
Protein: OXM
Technology: RevPEG

Long-acting Oxyntomodulin for the treatment of obesity and diabetes, Phase 1 clinical trial was completed successfully

MOD-701

2006-2008
Protein: Epo
Technology: CTP

Long-acting Erythropoietin (EPO) for treatment of severe anemia in patients with chronic kidney disease and other hematologic disorders

MOD-801

2007-2008
Protein: GLP-1
Technology: CTP

Long-acting GLP-1 for the treatment of diabetes

MOD-901

2009-2010
Protein: IFNβ
Technology: CTP

Long-acting IFNβ for the treatment of MS-Multiple Sclerosis

MOD- 1101

2009-2010
Protein: ApoA1
Technology: CTP

Long-acting ApoA1 for the treatment of atherosclerosis

MOD-1201

2016- 2020
Protein: hGH antagonist
Technology: CTP

Long-acting Mutated growth hormone for treatment of acromegaly. Weekly dose to replace current daily treatment

MOD-1301

2016-2022
Protein: IGF1
Technology: CTP

Long-acting Insulin like growth factor for SPIGF1D- a form a dwarfism caused by insensitivity to hGH

MOD-1501

2016-2021
Protein: GLP2 analog
Technology: REV-PEG

Long-acting Glucagon like peptide-2 for treatment of short bowl syndrome

MOD-1601

2018- 2022
Protein: PTH
Technology: REV-PEG

Parathyroid hormone for treatment of hypoparathyroidism. Weekly dose instead of a daily dose